With so many STI testing services available online, it’s not always clear which one is the best fit for your needs. That’s why we’ve reviewed the top lab-based and at-home providers — looking at speed, support, cost, usability, and how easily you can access results.
Whether you prefer visiting a lab or testing from home, these reviews will help you quickly understand what each company offers, how the process works, and what sets them apart.
We’ve organized the reviews below by test format. If you’re planning to visit a lab in person, start with the first section. If you’re more interested in mail-in kits that you can use from home, scroll down to explore those options next.
Lab-Based STI Testing Services
Lab-based STI testing typically involves visiting a certified location for blood or urine collection. These providers offer speed, support, and accurate results without requiring insurance or referrals. Tests are ordered online, and most labs support walk-in availability or quick scheduling.
STDCheck
STDCheck is our top lab-based recommendation for fast, discreet testing. With 4,500+ U.S. locations, results in 1–2 days, and a focus on privacy, it’s ideal for those who want clinical accuracy without the clinic visit.
eNational Testing
eNational Testing supports same-day STI lab testing with walk-in flexibility and online ordering. No insurance or referrals required. Includes access to a clinical support line and physician follow-up if needed.
Priority STD
Priority STD offers fast, lab-based STI screening with a streamlined interface and quick turnaround. Results are typically available in 1–3 days with encrypted digital access.
PersonaLabs
PersonaLabs partners with major lab networks to offer à la carte STI testing. You can book online and visit thousands of lab locations nationwide without a doctor’s referral.
HealthLabs
HealthLabs offers customizable STI panels through partnerships with CLIA-certified labs. No insurance is needed, and most tests can be completed same-day at one of 4,500+ locations.
Quest Diagnostics
Quest Diagnostics is one of the largest lab networks in the country. If your provider routes through Quest, you’ll get secure digital results and easy appointment booking online.
LabCorp
LabCorp is another national lab partner that supports STI testing through affiliated providers. They offer in-person sample collection, results via portal, and widespread U.S. availability.
At-Home STI Test Kits
At-home STI test kits let you collect your own sample in private and send it to a certified lab. Most services include prepaid shipping, online results, and treatment options — all without a clinic visit.
myLAB Box
myLAB Box is our top pick for at-home STI testing. They offer a wide selection of test kits, discreet shipping, fast turnaround, and an excellent customer dashboard for results access.
Simple HealthKit
Simple HealthKit provides affordable at-home STI kits with fast lab results, an intuitive ordering process, and optional clinical guidance for positive results.
AccugeneDX
AccugeneDX focuses on basic STI kits at a low cost. They provide simple sample collection, secure digital results, and a clean Amazon checkout experience.
247Labkit
247Labkit offers basic STI screening kits for common infections. The process is straightforward, results come fast, and pricing is among the lowest for at-home testing.
Everlywell
Everlywell is a well-known wellness brand offering mail-in STI kits. Their kits are easy to use and results are reviewed by licensed physicians — but pricing tends to be higher than competitors.